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Only one subject (4.2%) improved to normal status

Coffee, caffeine, and risk of hospitalization for arrhythmias

These gastrointestinal effects are typically most pronounced during the first few weeks at each dose level and tend to improve as the body adjusts

This phenomenon is largely caused by the decrease in estrogen levels, which causes the hypothalamus (the part of the brain that regulates body temperature) to become more sensitive to slight changes in body temperature